Let It Encrypt (LIE)

Winter pressures. Let it flow, let it flow, let it flow.

Neurons let it slide

During mammalian brain development, many neurons migrate away from the site where they are born to settle in distant locations where they send out dendrites and axons to connect with other neurons. Both neuronal migration and axon/dendrite extension depend on forces generated by microtubule-based motor proteins such as cytoplasmic dynein. The effects of these forces depend, however, on the orga...

Let it snow! Let it snow! Let it snow! Estimating cocaine production using a novel dataset based on reported seizures of laboratories

Background: data on cocaine market appear to be inconsistent, as they tend to show declining prices vis a vis a steady or increasing demand and a declining supply. This paper proposes an explanation by providing evidence of an under-estimation of the supply of cocaine. Methods: we put forwa d a conservative estimate of cocaine production in Colombia for year 2008 by means of reported seizures o...

Let it snow! Let it snow! Let it snow! Estimating cocaine production using a novel dataset based on reported seizures of laboratories in Colombia.

BACKGROUND Data on the cocaine market appear inconsistent, as they tend to show declining prices vis-a-vis steady or increasing demand and a declining supply. This paper proposes an explanation for this trend by providing evidence of an under-estimation of the supply of cocaine. METHODS We propose a conservative estimate of cocaine production in Colombia for 2008, using data based on all repo...

Let Sleeping Zebrafish Lie: A New Model for Sleep Studies

Although the function of sleep is hotly debated, one thing is clear—we, and most other animals, cannot do without it. In a new study, Yokogawa et al. describe how zebrafi sh sleep, fi nding both striking similarities to mammalian sleep and its regulation and intriguing differences. How can you tell when a zebrafi sh is asleep? According to Yokogawa et al., it stops swimming (for at least six se...